Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

SG Potkin, G Guffanti, A Lakatos, JA Turner, F Kruggel… - PloS one, 2009 - journals.plos.org
Background With the exception of APOE ε4 allele, the common genetic risk factors for
sporadic Alzheimer's Disease (AD) are unknown. Methods and Findings We completed a
genome-wide association study on 381 participants in the ADNI (Alzheimer's Disease
Neuroimaging Initiative) study. Samples were genotyped using the Illumina Human610-
Quad BeadChip. 516,645 unique Single Nucleotide Polymorphisms (SNPs) were included
in the analysis following quality control measures. The genotype data and raw genetic data …

[PDF][PDF] Hippocampal atrophy as a quantitative trait in a genome-wide association study

SG Potkin, G Guffanti, A Lakatos, JA Turner, F Kruggel… - 2009 - scienceopen.com
Background: With the exception of APOE e4 allele, the common genetic risk factors for
sporadic Alzheimer's Disease (AD) are unknown. Methods and Findings: We completed a
genome-wide association study on 381 participants in the ADNI (Alzheimer's Disease
Neuroimaging Initiative) study. Samples were genotyped using the Illumina Human610-
Quad BeadChip. 516,645 unique Single Nucleotide Polymorphisms (SNPs) were included
in the analysis following quality control measures. The genotype data and raw genetic data …
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