There are reports of patients with sickle cell disease who developed hematological
malignancies but the relationship between these malignancies and sickle cell disease
(SCD) is not yet defined. The co-existence of a hematological malignancy with SCD poses
certain challenges for the management of each condition. We describe a 7-year-old boy with
sickle cell anemia who developed Hodgkin's lymphoma and the challenges of management.
He presented with a 4-year history of bilateral neck swelling and a 2-month history of weight …

To study the co existence of Hodgkins lymphoma in sickle cell disease in a 10-year-old boy
who is also a known case of sickle cell anaemia presented to out centre with symptoms of
fever, weight loss. History of previous blood transfusions was given. On clinical examination,
he was found to have pallor, generalised lymphadenopathy, splenomegaly. Complete blood
picture revealed haemoglobin of 9 g/dl, white blood cell count of 12,000/cu mm, platelet
count of 2 lakhs. Biopsy from the cervical lymph node revealed effacement of lymph nodal …