[HTML][HTML] How does SARS-CoV-2 targets the elderly patients? A review on potential mechanisms increasing disease severity
A Smorenberg, EJG Peters, PLA van Daele… - European Journal of …, 2021 - Elsevier
Abstract Importance: Among COVID-19 cases, especially the (frail) elderly show a high
number of severe infections, hospital admissions, complications, and death. The highest
mortality is found between 80 and 89 years old. Why do these patients have a higher risk of
severe COVID-19? In this narrative review we address potential mechanisms regarding viral
transmission, physical reserve and the immune system, increasing the severity of this
infection in elderly patients. Observations: First, the spread of COVID-19 may be enhanced …
number of severe infections, hospital admissions, complications, and death. The highest
mortality is found between 80 and 89 years old. Why do these patients have a higher risk of
severe COVID-19? In this narrative review we address potential mechanisms regarding viral
transmission, physical reserve and the immune system, increasing the severity of this
infection in elderly patients. Observations: First, the spread of COVID-19 may be enhanced …
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