您是不是要找: How estrogen fueled breast cancer

How estrogen fuels breast cancer

A Rana, V Rangasamy, R Mishra - Future Oncology, 2010 - Taylor & Francis
… in breast cancer is that estrogen promotes the survival of ER + breast cancer cells by … growth
and could prove beneficial for ER + breast cancer treatment. Recently, we have identified a …

Can environmental estrogens cause breast cancer?

D Lee Davis, HL Bradlow - Scientific American, 1995 - JSTOR
… First, potential estrogenicity should be assessed for materials that play critical roles in our
society, such as fuels, drugs and plastics» and for any proposed substitute agents. Second, the …

Fat may fuel breast cancer growth

K Hede - 2008 - academic.oup.com
breast cancer—like estrogen, insulin, and leptin—have provided clues to why excess body
weight appears to encourage breast cancer … fat tissue, such as estrogen, insulin, and insulin-…

The new biology of estrogen-induced apoptosis applied to treat and prevent breast cancer

VC Jordan - Endocrine-related cancer, 2014 - pmc.ncbi.nlm.nih.gov
… any cancer. This review documents the clinical use of estrogen for breast cancer treatment
or estrogen replacement … The fact that estrogen is implicated as the “fuel for the fire” of breast

Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

UE Martinez-Outschoorn, AF Goldberg… - Cancer biology & …, 2011 - Taylor & Francis
Here, we show that tamoxifen resistance is induced by cancer-associated fibroblasts (CAFs).
Coculture of estrogen receptor positive (ER+) MCF7 cells with fibroblasts induces …

Bioenergetic differences between MCF-7 and T47D breast cancer cells and their regulation by oestradiol and tamoxifen

BN Radde, MM Ivanova, HX Mai, JK Salabei… - Biochemical …, 2015 - portlandpress.com
… ’ by deriving fuel, … oestrogen regulation of mt function remain largely undefined [10,11].
Recent studies showed that growing MCF-7 luminal A, oestrogen receptor α (ERα)+ breast cancer

How far have we come in terms of estrogens in breast cancer?

KM McNamara, F Guestini, M Sakurai, K Kikuchi… - Endocrine …, 2016 - jstage.jst.go.jp
… These studies indicated that an upregulation of 17βHSD1 and/or loss of 17βHSD2 could
possibly contribute to the maintenance of high estrogens than subsequently fuel carcinoma

Fuel, electricity, ER and HER2—a hybrid-car model of breast cancer

S Saji, F Sato, NT Ueno - Nature Reviews Clinical Oncology, 2012 - nature.com
… We propose here that the complex breast cancer model can be understood by comparing it
… about breast cancer biology, the two main power sources in breast cancer are the oestrogen

Estrogen down-regulates uncoupling proteins and increases oxidative stress in breast cancer

J Sastre-Serra, A Valle, MM Company, I Garau… - Free Radical Biology …, 2010 - Elsevier
… During oxidative phosphorylation single electrons derived from metabolic fuels flow along
the electron transport chain to the final electron acceptor, molecular oxygen, which is reduced …

Obesity and breast cancer–Role of estrogens and the molecular underpinnings of aromatase regulation in breast adipose tissue

C Gerard, KA Brown - Molecular and cellular endocrinology, 2018 - Elsevier
… and estrogen biosynthesis … breast cancer, highlighting the different molecular mechanisms
and metabolic pathways involved in aromatase regulation, estrogen production and breast
您是不是要找: How estrogen fueled breast cancer