known human ã2 herpesvirus (rhadinovirus) and the most recently discovered tumor virus.
KSHV is associated with Kaposi's sarcoma and two other lymphoproliferative disorders in
the AIDS setting: primary effusion lymphoma and the plasma cell variant of multicentric
Castleman's disease. This review offers an update on the epidemiology and the role of
KSHV genes in the development of disease.