[HTML][HTML] Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets

…, K Powell, A Amini, SL Irwin, H Ferry, T Ambrose… - Cell reports, 2021 - cell.com
… However, transcriptional heterogeneity of human intestinal T RM cellstranscriptional and
functional heterogeneity of human T RM cells through study of donor-derived T RM cells from …

Human tissue-resident memory T cells are defined by core transcriptional and functional signatures in lymphoid and mucosal sites

…, M Miron, T Granot, RS Guyer, DJ Carpenter, T Senda… - Cell reports, 2017 - cell.com
… tissue memory T cells constitute a distinct subset in diverse mucosal and lymphoid tissues. …
a core transcriptional profile within the CD69 + subset of memory CD4 + and CD8 + T cells in …

Regulation of intestinal tissueresident memory T cells: a potential target for inflammatory bowel disease

X Xia, Z Huang, C Xu, H Fu, S Wang, J Tian… - Cell Communication and …, 2024 - Springer
cells from small intestine and colon exhibited distinctive patterns of cytokine and granzyme
expression along with substantial transcriptional and functional … in TRM cells mainly include

Intestinal CD8+ tissueresident memory T cells: From generation to function

L Cheng, S Becattini - European Journal of Immunology, 2022 - Wiley Online Library
… long-lived memory CD8 + T cells via pathways that include, but are … of the functional capabilities
of intestinal Trm versus T cells in … , transcriptional landscape, and functional properties of …

Tissue-resident memory T cells: decoding intra-organ diversity with a gut perspective

M Murakami - Inflammation and Regeneration, 2024 - Springer
… of T RM have elucidated the transcriptional and functional … RM in the gut, which constitute
the largest and most intricate … their pathological relevance to gut inflammation in humans. …

An overview of tissue-resident memory T cells in the intestine: from physiological functions to pathological mechanisms

Y Lyu, Y Zhou, J Shen - Frontiers in immunology, 2022 - frontiersin.org
… In fact, most memory T cells in the intestinal mucosa possess … transcriptional profiles (6–8),
implicating the significance of T … CD73, two key functional markers of regulatory T cells (76). …

Axes of heterogeneity in human tissueresident memory T cells

PA Szabo - Immunological Reviews, 2023 - Wiley Online Library
… same phenotypic, transcriptional, and functional features of … migration or include endogenous
memory T cells that fail to … , transcriptional, and functional states of TRM (eg, intestines). …

[HTML][HTML] Heterogeneity of tissue resident memory T cells

Š Konjar, X Ficht, M Iannacone, M Veldhoen - Immunology Letters, 2022 - Elsevier
… to one that initiates transcriptional programmes and rapid cell … with memory CD8 T cells
found in functionally distinct subsets … In CD103 + CD69 + memory T cells in human colon were …

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

DJ Topham, EC Reilly - Frontiers in immunology, 2018 - frontiersin.org
… (DCs) plays a similar functional role of maintaining them within the organ (38, 39). While … ,
gut, and respiratory tissues. Transcriptional regulation is different in mouse and human systems…

Characteristics of CD8+ and CD4+ TissueResident Memory Lymphocytes in the Gastrointestinal Tract

P Li, Y Zhang, Y Xu, H Cao, L Li - … Gut & Microbiome Research, 2022 - Wiley Online Library
… As major transcriptional regulators of TCM and TEM cells, T-… birth, comprising one third of
intraepithelial lymphocyte population … or functional characteristics of GI-resident CD8 + T cells. …