Humoral responses in human strongyloidiasis: correlations with infection chronicity

NS Atkins, JF Lindo, MG Lee, DJ Conway… - Transactions of the …, 1997 - Elsevier
Strongyloides stercoralis L3-specific antibody isotype responses amongst individuals with
known long-standing (28–46 years) infection were compared with those of 'young'(6–29
years of age) and 'old'(30–80 years of age) infected individuals from an endemic Jamaican
population. Characterization of age-dependent isotype patterns in the endemic community
showed that immunoglobulin (Ig) G1 responses were significantly inversely correlated with
age. Additionally, a trend towards lower IgE levels in the older age group was observed …
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