Hybrid electron microscopy normal mode analysis graphical interface and protocol

COS Sorzano, JM de La Rosa-Trevín, F Tama… - Journal of structural …, 2014 - Elsevier
This article presents an integral graphical interface to the Hybrid Electron Microscopy
Normal Mode Analysis (HEMNMA) approach that was developed for capturing continuous
motions of large macromolecular complexes from single-particle EM images. HEMNMA was
shown to be a good approach to analyze multiple conformations of a macromolecular
complex but it could not be widely used in the EM field due to a lack of an integral interface.
In particular, its use required switching among different software sources as well as selecting …
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