Identification and characterization of genes responsible for biosynthesis of kojic acid, an industrially important compound from Aspergillus oryzae
Y Terabayashi, M Sano, N Yamane, J Marui… - Fungal Genetics and …, 2010 - Elsevier
Kojic acid is produced in large amounts by Aspergillus oryzae as a secondary metabolite
and is widely used in the cosmetic industry. Glucose can be converted to kojic acid, perhaps
by only a few steps, but no genes for the conversion have thus far been revealed. Using a
DNA microarray, gene expression profiles under three pairs of conditions significantly
affecting kojic acid production were compared. All genes were ranked using an index
parameter reflecting both high amounts of transcription and a high induction ratio under …
and is widely used in the cosmetic industry. Glucose can be converted to kojic acid, perhaps
by only a few steps, but no genes for the conversion have thus far been revealed. Using a
DNA microarray, gene expression profiles under three pairs of conditions significantly
affecting kojic acid production were compared. All genes were ranked using an index
parameter reflecting both high amounts of transcription and a high induction ratio under …
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