inflammatory conditions, thereby contributing to host defense and tissue pathology. A
common monocyte progenitor (cMoP) that is strictly committed to the monocyte lineage has
been recently identified in mice. Here, we identified human cMoPs as a CLEC12A hi CD64
hi subpopulation of conventional granulocyte-monocyte progenitors (cGMPs) in umbilical
cord blood and in bone marrow. Human cMoPs gave rise to monocyte subsets without …