Identification of a three‐miRNA signature as a novel potential prognostic biomarker in patients with clear cell renal cell carcinoma

Y Luo, L Chen, G Wang, Y Xiao, L Ju… - Journal of Cellular …, 2019 - Wiley Online Library
Current studies suggest that some microRNAs (miRNAs) are associated with prognosis in
clear cell renal cell carcinoma (ccRCC). In this paper, we aimed to identify a miRNAs
signature to improve prognostic prediction for ccRCC patients. Using ccRCC RNA‐Seq data
of The Cancer Genome Atlas (TCGA) database, we identified 177 differentially expressed
miRNAs between ccRCC and paracancerous tissue. Then all the ccRCC tumor samples
were divided into training set and validation set randomly. Three‐miRNA signature including …

[HTML][HTML] Identification of a three miRNA signature as a novel potential prognostic biomarker in patients with bladder cancer

F Peng, H Li, H Xiao, L Li, Y Li, Y Wu - Oncotarget, 2017 - ncbi.nlm.nih.gov
There is not a good biomaker that is closely related to survival time for bladder cancer
(BLCA), The aim of the study is to identify a miRNA signature that could predict prognosis in
BLCA patients according to the data from The Cancer Genome Atlas (TCGA). a total of 377
BLCA patients were finally enrolled in the study. The three miRNA signature was identified
by Multivariate Cox proportional hazards analyses that common clinical variables were
controled. The three microRNA signature showed greater predicting prognosis capacity for …
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