Immune modulation of hair follicle regeneration
The mammalian hair follicle undergoes repeated bouts of regeneration orchestrated by a
variety of hair follicle stem cells. The last decade has witnessed the emergence of the
immune niche as a key regulator of stem cell behavior and hair follicle regeneration. Hair
follicles chemotactically attract macrophages and T cells so that they are in range to regulate
epithelial stem cell quiescence, proliferation and differentiation during physiologic and
injured states. Disruption of this dynamic relationship leads to clinically significant forms of …
variety of hair follicle stem cells. The last decade has witnessed the emergence of the
immune niche as a key regulator of stem cell behavior and hair follicle regeneration. Hair
follicles chemotactically attract macrophages and T cells so that they are in range to regulate
epithelial stem cell quiescence, proliferation and differentiation during physiologic and
injured states. Disruption of this dynamic relationship leads to clinically significant forms of …
Immune modulation of hair follicle regeneration
R Waleed, S Sarthak, B Jeff - NPJ Regenerative Medicine, 2020 - search.proquest.com
The mammalian hair follicle undergoes repeated bouts of regeneration orchestrated by a
variety of hair follicle stem cells. The last decade has witnessed the emergence of the
immune niche as a key regulator of stem cell behavior and hair follicle regeneration. Hair
follicles chemotactically attract macrophages and T cells so that they are in range to regulate
epithelial stem cell quiescence, proliferation and differentiation during physiologic and
injured states. Disruption of this dynamic relationship leads to clinically significant forms of …
variety of hair follicle stem cells. The last decade has witnessed the emergence of the
immune niche as a key regulator of stem cell behavior and hair follicle regeneration. Hair
follicles chemotactically attract macrophages and T cells so that they are in range to regulate
epithelial stem cell quiescence, proliferation and differentiation during physiologic and
injured states. Disruption of this dynamic relationship leads to clinically significant forms of …
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