… -borne filarial nematodes cause the severe, debilitating disease of human lymphatic
filariasis. In areas endemic for this disease, differential responses range from putative immunity …

… on immune evasion by filarial nematodes, which infest the lymphatic system of mammals. …
filarial worms live in a milieu bathed in immune effector cells, antibodies and other immune …

… In humans and probably other mammalians that are the specific hosts to filarial nematodes,
immune deviation seems to start already before birth: for both onchocerciasis and lymphatic …

… filarial infections are well documented, the host immune determinants ie, mechanisms that
lead to killing huge multicellular parasites such as filarial nematodes… of filarial nematodes, the …

… immune reactions. This review describes recent findings on innate immune evasion strategies
of parasitic nematodes … Infection of Aedes aegypti with the filarial parasite Brugia malayi …

… infections, suggesting a differential response of the host immune response to these filarial
nematodes 10. In LF, individuals presenting overt clinical pathologies such as lymphedema, …

… However, immune-dependant development by helminth parasites has so far eluded such …
arms of the immune response of experimental hosts, we show that filarial nematodes, the …

… As nematode genomes are relatively large (100 million bp or more) and encode … direct
immune modulation products is immense. Second, nematode parasites such as the filariae can …

… This analysis also reveals that immune genes and immune pathway target genes are strongly
activated in Malpighian tubules following D. immitis infection. We found that all gene sets, …

… nematodes, filariae are non-replicating parasites which cannot rapidly overwhelm or outflank
the immune … Second, these worms are physically extremely large targets for the immune sys…