Immuno-informatics study identifies conserved T cell epitopes in non-structural proteins of Bluetongue virus serotypes: formulation of a computationally optimized next …

…, R Hebbandi Nanjunadappa, T Karakach… - Frontiers in …, 2024 - frontiersin.org
… into an in silico-based multi-epitope BTV vaccine. In our strategy, we emphasize T cell
epitopes over B cell epitopes due to their documented ability to induce cross-reactive T cell-…

Immunoinformatics designed T cell multi epitope dengue peptide vaccine derived from non structural proteome

S Krishnan, A Joshi, N Akhtar, V Kaushik - Microbial Pathogenesis, 2021 - Elsevier
… Then the identified epitopes and the HLA 3D structure … Only 10% 9 mer conserved T cell
epitopes were found potential … /97-111 are subjected to intensive Immuno-informatics analysis. …

Immunoinformatic approach to design a multiepitope vaccine targeting non-mutational hotspot regions of structural and non-structural proteins of the SARS CoV2

V Solanki, M Tiwari, V Tiwari - PeerJ, 2021 - peerj.com
identified seven (structural and non-structural) proteins of this … T lymphocytes epitope
predictions of all seven proteins were … However, current reverse immuno-informatics approaches …

Immuno-informatics-based identification of novel potential b cell and t cell epitopes to fight zika virus infections

W Ezzemani, MP Windisch, A Kettani… - … Current Drug Targets …, 2021 - ingentaconnect.com
… NS5 protein (~103 kDa) is the largest and best-preserved vi… proteins (capsid and envelope)
and three non-structural … al., identified putative epitopes in the E, NS1, NS3, and NS5 …

Exploring rotavirus proteome to identify potential B-and T-cell epitope using computational immunoinformatics

YD Devi, A Devi, H Gogoi, B Dehingia, R Doley… - Heliyon, 2020 - cell.com
immuno-informatics approaches were applied and identified 28 … B-cells, 26 conformational
B-cell, 44 T C cell and 40 T H cell binding epitopes for structural and non-structural proteins of …

Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review

Z Noorimotlagh, C Karami, SA Mirzaee… - International …, 2020 - Elsevier
… CoVs encodes multiple structural and non-structural proteins… -step’ studies and the number
of studies identified for this review… B and T cell epitopes are highly conserved between SARS-…

Design of a novel multi-epitope vaccine candidate against hepatitis C virus using structural and nonstructural proteins: An immunoinformatics approach

E Behmard, HT Abdulabbas, S Abdalkareem Jasim… - PLoS …, 2022 - journals.plos.org
T Lymphocyte (HTL)) epitopes The IEDB tool was used to predict HTL epitopes in structural
and non-structural proteinsImmuno-informatics analysis of PAKISTAN-based HCV subtype-…

Epitope-based therapeutic targets in HCV genotype 1 non-structural proteins: a novel strategy to combat emerging drug resistance

M Tudi, A Sawuti, M Abudurusuli, C Wu… - Frontiers in Cellular …, 2024 - frontiersin.org
… to predict cytotoxic T lymphocyte (CTL) epitopes. Following this, … Results: The study identified
27 potential CTL epitopes from … immunoinformatics analyses, we identified 27 lead epitopes

T-cell epitope vaccine design by immunoinformatics

A Patronov, I Doytchinova - Open biology, 2013 - royalsocietypublishing.org
… promiscuous (for a given HLA superfamily) peptides, and Conservatrix determines unchanged
(conserved) regions in the proteins of the mutant pathogens of the same species [120]. …

Immunoinformatics mapping of potential epitopes in SARS-CoV-2 structural proteins

YD Devi, HB Goswami, S Konwar, C Doley, A Dolley… - PLoS …, 2021 - journals.plos.org
… helper T lymphocytes (HTL) and B-cell epitopes were joined … , and some non-structural
proteins contribute to CD8+ T-cell … aa 58–68) proteins are both conserved and common in the two …