… protein or full-length spike (S) protein-based vaccines. Here, we investigated the immunogenicity
of naked DNA vaccines expressing different fragments of MERS-CoV S protein in mice. …

… the group immunized with the DNA vaccine encoding the full-length S protein presented a
reduced … Similar to the MERS-CoV DNA vaccine, the S1 antigen showed higher NAb titers and …

… adenovirus vector vaccine (ChAdOx1) and a DNA vaccine (… immunogenicity of MERS-CoV
RBD-based subunit vaccines … S candidate vaccines against MERS-CoV infection, careful …

… and other pathogenic human CoVs such as MERS-CoV and SARS-CoV have … based
vaccines target the S1 subunit, making S1 an attractive and probably safer immunogen for vaccine …

… To test the immunogenicity of our vaccine candidates against multiple MERS-CoV strains—…
on the surface of transduced cells after DNA immunization may have contributed to the …

… immunogenicity of MERS-CoV S subunits as a DNA vaccine, human codon-optimized pSΔER,
pSΔTM, pS1, pRBD, and pS2 DNA … vaccine candidates (pSΔER DNA prime-SΔTM protein …

… immunization of small and large animal models with DNA vaccines encoding MERS-CoV
spike (S) protein … In subjects immunized with INO-4700 (MERS-CoV S protein DNA vaccine) …

… immunization in animal models with DNA vaccines encoding MERS-CoV spike (S) protein
… In subjects immunized with MERS-CoV DNA vaccine durable neutralizing antibodies (nAbs) …

… of GLS-5300, the first DNA vaccine candidate against MERS coronavirus to enter clinical
trials. … it remains difficult to interpret the relevance of the immunogenicity parameters that were …

… An ideal MERS vaccine candidate should have high immunogenicity and strong potency, as
… Since such DNA vaccines encode MERS-CoV full-length S protein, the potential induction …