Immunological principles regulating immunomodulation with biomaterials
The immune system has evolved to recognize and eliminate pathogens; this recognition
relies on the identification of structural molecular patterns within unique tissue
microenvironments. Therefore, bioengineers can harness these immunological cues to
design materials that modulate innate and adaptive immunity in a controlled manner. This
review acts as an immunology primer by focusing on the basic molecular and cellular
immunology principles governing immunomodulation with biomaterials.
relies on the identification of structural molecular patterns within unique tissue
microenvironments. Therefore, bioengineers can harness these immunological cues to
design materials that modulate innate and adaptive immunity in a controlled manner. This
review acts as an immunology primer by focusing on the basic molecular and cellular
immunology principles governing immunomodulation with biomaterials.
Abstract
The immune system has evolved to recognize and eliminate pathogens; this recognition relies on the identification of structural molecular patterns within unique tissue microenvironments. Therefore, bioengineers can harness these immunological cues to design materials that modulate innate and adaptive immunity in a controlled manner. This review acts as an immunology primer by focusing on the basic molecular and cellular immunology principles governing immunomodulation with biomaterials.
Elsevier
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