Impact of a new sampling buffer on faecal haemoglobin stability in a colorectal cancer screening programme by the faecal immunochemical test

G Grazzini, L Ventura, T Rubeca, S Rapi… - European Journal of …, 2017 - journals.lww.com
Haemoglobin (Hb) stability in faecal samples is an important issue in colorectal cancer
screening by the faecal immunochemical test (FIT) for Hb. This study evaluated the
performance of the FIT-Hb (OC-Sensor Eiken) used in the Florence screening programme
by comparing two different formulations of the buffer, both in an analytical and in a clinical
setting. In the laboratory simulation, six faecal pools (three in each buffer type) were stored
at different temperatures and analysed eight times in 10 replicates over 21 days. In the …
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