Impact of a probiotic-based cleaning intervention on the microbiota ecosystem of the hospital surfaces: focus on the resistome remodulation
Background Contamination of hospital surfaces by clinically-relevant pathogens represents
a major concern in healthcare facilities, due to its impact on transmission of healthcare-
associated infections (HAIs) and to the growing drug resistance of HAI-associated
pathogens. Routinely used chemical disinfectants show limitations in controlling pathogen
contamination, due to their inefficacy in preventing recontamination and selection of
resistant strains. Recently we observed that an innovative approach, based on a cleanser …
a major concern in healthcare facilities, due to its impact on transmission of healthcare-
associated infections (HAIs) and to the growing drug resistance of HAI-associated
pathogens. Routinely used chemical disinfectants show limitations in controlling pathogen
contamination, due to their inefficacy in preventing recontamination and selection of
resistant strains. Recently we observed that an innovative approach, based on a cleanser …
Impact of a Probiotic-Based Cleaning Intervention on the Microbiota Ecosystem of the Hospital Surfaces: results of the first multicentre and pre-post intervention …
E Caselli - CIMT-Centre for Innovative Medical Technology; CIMT …, 2016 - sfera.unife.it
Contamination of hospital surfaces can contribute to transmission of healthcare-associated
infections (HAIs), representing a global concern. Chemicals-based cleaning shows
limitations in controlling surface bioburden, and can select resistant species. Recently, a
system based on detergents containing probiotics of the spore-forming Bacillus genus
(PCHS) was shown to decrease surface pathogens up to 90% more than conventional
disinfectants. PCHS system was also evaluated for its impact on the drug-resistance features …
infections (HAIs), representing a global concern. Chemicals-based cleaning shows
limitations in controlling surface bioburden, and can select resistant species. Recently, a
system based on detergents containing probiotics of the spore-forming Bacillus genus
(PCHS) was shown to decrease surface pathogens up to 90% more than conventional
disinfectants. PCHS system was also evaluated for its impact on the drug-resistance features …
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