The design process of an object, system or space must consider the physical, mental and psychological traits of its intended users. Moreover, the results of the design process are also defined by the attributes related to the context. However, current product design approaches does not offer a proper balance among the “human”, “artefact” and “context” dimensions. Consequently, a product design methodology that covers the overall Human-Artefact-Context system, from a cognitive and physical ergonomics point of view, is proposed. The generalization of the proposal is based on a synergic structure of User-Centered Design methodologies and ergonomic criteria that prevails throughout the product development stages. The latter ensures a better adaptation to specific context and user needs in a way that improves efficiency, security and consumer well-being.