A two‐compartment exchange model for perfusion quantification using arterial spin labeling
(ASL) is presented, which corrects for the assumption that the capillary wall has infinite
permeability to water. The model incorporates an extravascular and a blood compartment
with the permeability surface area product (PS) of the capillary wall characterizing the
passage of water between the compartments. The new model predicts that labeled spins
spend longer in the blood compartment before exchange. This makes an accurate blood T1 …

Improved accuracy of human cerebral blood perfusion measurements using arterial spin
labeling : accounting for capillary water permeability | CiNii Research … Improved accuracy
of human cerebral blood perfusion measurements using arterial spin labeling : accounting
for capillary water permeability …