Multidrug resistance (MDR) is the dominant cause of the failure of cancer chemotherapy.
The design of antitumor drugs that are able to evade MDR is rapidly evolving, showing that
this area of biomedical research attracts great interest in the scientific community. The
current review explores promising recent approaches that have been developed with the
aim of circumventing or overcoming MDR. Encouraging results have been obtained in the
investigation of the MDR-modulating properties of various classes of natural compounds …