In Silico Analysis Identified Putative Pathogenic Missense nsSNPs in Human SLITRK1 Gene
Human DNA contains several variations, which can affect the structure and normal
functioning of a protein. These variations could be single nucleotide polymorphisms (SNPs)
or insertion-deletions (InDels). SNPs, as opposed to InDels, are more commonly present in
DNA and may cause genetic disorders. In the current study, several bioinformatic tools were
used to prioritize the pathogenic variants in the SLITRK1 gene. Out of all of the variants, 16
were commonly predicted to be pathogenic by these tools. All the variants had very low …
functioning of a protein. These variations could be single nucleotide polymorphisms (SNPs)
or insertion-deletions (InDels). SNPs, as opposed to InDels, are more commonly present in
DNA and may cause genetic disorders. In the current study, several bioinformatic tools were
used to prioritize the pathogenic variants in the SLITRK1 gene. Out of all of the variants, 16
were commonly predicted to be pathogenic by these tools. All the variants had very low …
[PDF][PDF] In Silico Analysis Identified Putative Pathogenic Missense nsSNPs in Human SLITRK1 Gene. Genes 2022, 13, 672
Human DNA contains several variations, which can affect the structure and normal
functioning of a protein. These variations could be single nucleotide polymorphisms (SNPs)
or insertion-deletions (InDels). SNPs, as opposed to InDels, are more commonly present in
DNA and may cause genetic disorders. In the current study, several bioinformatic tools were
used to prioritize the pathogenic variants in the SLITRK1 gene. Out of all of the variants, 16
were commonly predicted to be pathogenic by these tools. All the variants had very low …
functioning of a protein. These variations could be single nucleotide polymorphisms (SNPs)
or insertion-deletions (InDels). SNPs, as opposed to InDels, are more commonly present in
DNA and may cause genetic disorders. In the current study, several bioinformatic tools were
used to prioritize the pathogenic variants in the SLITRK1 gene. Out of all of the variants, 16
were commonly predicted to be pathogenic by these tools. All the variants had very low …