In silico epitope analysis of unique and membrane associated proteins from Mycobacterium avium subsp. paratuberculosis for immunogenicity and vaccine evaluation
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of
paratuberculosis disease affecting ruminants worldwide. The aim of this study was to identify
potential candidate antigens and epitopes by bio and immuno-informatic tools which could
be later evaluated as vaccines and/or diagnosis. 110 protein sequences were selected from
MAP K-10 genome database: 48 classified as putative enzymes involved in surface
polysaccharide and lipopolysaccharide synthesis, as membrane associated and secreted …
paratuberculosis disease affecting ruminants worldwide. The aim of this study was to identify
potential candidate antigens and epitopes by bio and immuno-informatic tools which could
be later evaluated as vaccines and/or diagnosis. 110 protein sequences were selected from
MAP K-10 genome database: 48 classified as putative enzymes involved in surface
polysaccharide and lipopolysaccharide synthesis, as membrane associated and secreted …
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