In silico study of potential organosulfur and flavonoids compounds in garlic (Allium sativum L.) as inhibitor of α-glucosidase enzyme

NAM Sa'adah, B Aulia, DN Ramadhani… - AIP Conference …, 2023 - pubs.aip.org
Diabetes mellitus is a chronic metabolic syndrome characterized by hyperglycemia due to
insulin-resistant, deficiency insulin secretion, or both. Patients need to ta e antidiabetic drugs
to control the glycemic index, one of them by inhibiting the α-glucosidase enzyme. Single
garlic (Allium sativum L.) has high bioactive compounds such as organosulfur and
flavonoids that may inhibit the α-glucosidase activity. This study aims to predict the potential
of organosulfur and flavonoids compounds of A. sativum L. in inhibiting α-glucosidase by in …
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