[引用][C] In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model

EL Zavjalov, IA Razumov, LA Gerlinskaya… - Vavilov J. Genet. Breed, 2015

[PDF][PDF] In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model

ЕЛ Завьялов, ИА Разумов, ЛА Герлинская… - 2015 - sites.icgbio.ru
Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer with the
average lifespan of patients about 9–12 months. The study of tumor formation and the
evaluation of new therapies for GBM require accurate and reproducible experimental brain
tumor animal models. In this study we used MRI for investigation of tumor morphology and
growth dynamic in an orthopic xenotransplantation immunodeficient mouse model (SCID
mouse line). Comparison of T1-and T2-weighed MRI scans preformed with a high-field MRI …
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