In-vitro evaluation of virulence markers and antifungal resistance of clinical Candida albicans strains isolated from Karachi, Pakistan

G Jabeen, SA Naz, DEN Rangel, N Jabeen… - Fungal Biology, 2023 - Elsevier
Candidiasis is a significant fungal infection with high mortality and morbidity rates
worldwide. Candida albicans is the most dominant species responsible for causing different
manifestations of candidiasis. Certain virulence traits as well as its resistance to antifungal
drugs contribute to the pathogenesis of this yeast. This study was designed to determine the
production of some virulence factors, such as biofilm formation and extracellular hydrolytic
enzymes (esterase, coagulase, gelatinase, and catalase) by this fungus, as well as its …
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