Increased daily handling of ovariectomized rats enhances performance on a radial-maze task and obscures effects of estradiol replacement

J Bohacek, JM Daniel - Hormones and behavior, 2007 - Elsevier
Estrogen impacts performance on tasks of learning and memory, although there are
inconsistencies in the direction and magnitude of the reported effects. Contributory factors to
the inconsistencies may be methodological differences associated with different regimens of
treatment. The goal of the present experiment was to assess the effect of increased
handling, such as that commonly associated with pharmacological or other experimental
manipulations, on the ability of estrogen to influence working memory performance. Young …
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