Increased end-expiratory pressures improve lung function in near-term newborn rabbits with elevated airway liquid volume at birth
EV McGillick, AB Te Pas… - Journal of Applied …, 2021 - journals.physiology.org
Approximately 53% of near-term newborns admitted to intensive care experience respiratory
distress. These newborns are commonly delivered by cesarean section and have elevated
airway liquid volumes at birth, which can cause respiratory morbidity. We investigated the
effect of providing respiratory support with a positive end-expiratory pressure (PEEP) of 8
cmH2O on lung function in newborn rabbit kittens with elevated airway liquid volumes at
birth. Near-term rabbits (30 days; term= 32 days) with airway liquid volumes that …
distress. These newborns are commonly delivered by cesarean section and have elevated
airway liquid volumes at birth, which can cause respiratory morbidity. We investigated the
effect of providing respiratory support with a positive end-expiratory pressure (PEEP) of 8
cmH2O on lung function in newborn rabbit kittens with elevated airway liquid volumes at
birth. Near-term rabbits (30 days; term= 32 days) with airway liquid volumes that …
Increased end-expiratory pressures improve lung function in near-term newborn 1 rabbits with elevated airway liquid volume at birth 2
MJ Kitchen - journals.physiology.org
NEW AND NOTEWORTHY: Term babies born by caesarean section have elevated airway
34 liquid volumes which predisposes them to respiratory distress. Treatments targeting
molecular 35 mechanisms to clear lung liquid are ineffective for term newborn respiratory
distress. We 36 showed that respiratory support with an end-expiratory pressure supports
lung function in 37 near-term rabbits with elevated airway liquid volumes at birth. This study
provides further 38 physiological understanding of lung function in newborns with elevated …
34 liquid volumes which predisposes them to respiratory distress. Treatments targeting
molecular 35 mechanisms to clear lung liquid are ineffective for term newborn respiratory
distress. We 36 showed that respiratory support with an end-expiratory pressure supports
lung function in 37 near-term rabbits with elevated airway liquid volumes at birth. This study
provides further 38 physiological understanding of lung function in newborns with elevated …
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