Increased risk of severe clinical course of COVID-19 in carriers of HLA-C* 04: 01

J Weiner, P Suwalski, M Holtgrewe, A Rakitko… - …, 2021 - thelancet.com
Background Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic,
there has been increasing urgency to identify pathophysiological characteristics leading to
severe clinical course in patients infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Human leukocyte antigen alleles (HLA) have been suggested
as potential genetic host factors that affect individual immune response to SARS-CoV-2. We
sought to evaluate this hypothesis by conducting a multicenter study using HLA sequencing …

[引用][C] Increased risk of severe clinical course of COVID‑19 in carriers of HLA‑C* 04: 01. EClinicalMedicine. 2021; 40: 101099

J Weiner, P Suwalski, M Holtgrewe, A Rakitko… - 2021 - PubMed
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