… We show here that by applying ICA to bladdercancertranscriptome data sets, exploiting … applied to multiple cancer types, it is possible to obtain insights into bladder carcinogenesis. …
… majority of bladdertumours at … to uncovering novel molecular biomarkers from bulk sequencing data that have an impact on clinical outcomes by analysing the data at the transcriptome …
SV Lindskrog, F Prip, P Lamy, A Taber… - Nature …, 2021 - nature.com
… The molecular landscape in non-muscle-invasive bladdercancer (NMIBC) is characterized by large … At the transcriptomics level, we identified four main classes of NMIBC with the …
… bulk transcriptome, which allows studying the properties of tumor … of bladdercancer, decomposition of bulk tumors into 20 … of independentcomponentanalysis to tumortranscriptomes …
K Meghani, Y Yu, N Frydenlund, EZ Li, B Choy… - bioRxiv, 2024 - biorxiv.org
… Employing phylogenetic analysis, we uncovered microbial species within the bladder TME of one … NanoString GeoMx human whole transcriptome atlas32 to differentiate tumor-specific …
ZD Shi, Z Sun, ZB Zhu, X Liu, JZ Chen… - Clinical and …, 2023 - Wiley Online Library
… landscape of recurrent BLCA are currently lacking. We sought to analyse whole-transcriptome data … Analysing the integrated data using principal componentanalysis (PCA) reduced the …
T Iyyanki, B Zhang, Q Wang, Y Hou, Q Jin, J Xu… - Genome biology, 2021 - Springer
… the genome-wide transcriptome, enhancer landscape, and … and basal subtypes of bladder cancer. Furthermore, we report … C in both bladdercancer cell lines and primary patient tumors. …
… bladdercancer patients by exploiting transcriptomeanalysis, … principal componentsanalysis (PCA) of the transcriptome data … genes may refine the molecular landscape, contributing to a …
… modules for such analysis. We apply independentcomponentanalysis to the large collection of … based on the human transcriptome (20,089 genes), and identified a set of 139 functional …