[HTML][HTML] Induction and maintenance of CX3CR1-intermediate peripheral memory CD8+ T cells by persistent viruses and vaccines

CL Gordon, LN Lee, L Swadling, C Hutchings, M Zinser… - Cell Reports, 2018 - cell.com
induction and maintenance of T cell memory is critical to the success of vaccines. A recently
described subset of memory CD8 + T cells … to vaccine-induced memory. We tracked these …

Induction and maintenance of CX3CR1-intermediate peripheral memory CD8 T cells by persistent viruses and novel vaccines

CL Gordon, LN Lee, L Swadling… - Available at SSRN …, 2018 - papers.ssrn.com
induction and maintenance of T-cell memory is critical to the success of novel vaccines. A
newly-described subset of memory CD8+ T-cells … on CD8+ memory T cells in persistent viral …

The cellular microenvironment regulates CX3CR1 expression on CD8+ T cells and the maintenance of CX3CR1+ CD8+ T cells

J Pokharel, I Shryki, AJ Zwijnenburg… - European Journal of …, 2024 - Wiley Online Library
… priming of naïve CD8+ T cells failed to robustly induce CX3CR1, … healthy human peripheral
blood mononuclear cells (PBMC) … memory CD8+ T cells. Having observed that in vitro primed …

[HTML][HTML] CX3CR1–CD8+ T cells are critical in antitumor efficacy but functionally suppressed in the tumor microenvironment

T Yamauchi, T Hoki, T Oba, H Saito, K Attwood… - JCI insight, 2020 - ncbi.nlm.nih.gov
… of dysfunctional states induced by persistent TCR stimulation… effector and memory CD8 + T
cells in the periphery in infectious … viral infection model (50), and support the notion that T cell

Identification of a T-bethi quiescent exhausted CD8 T cell subpopulation that can differentiate into TIM3+ CX3CR1+ effectors and memory-like cells

…, T Kurosaki, AT Satpathy, T Egawa - The Journal of …, 2021 - journals.aai.org
Persistent Ag induces a dysfunctional CD8 T cell state … + CX3CR1 + cells via a TIM3 − CX3CR1
+ intermediate (Fig. 2H). … % of CX3CR1 + CD8 T cells in the peripheral blood became tdT …

The Maintenance of CD4 and CD8 T Cell Response to Persistent Antigens

Y Xia - 2022 - openscholarship.wustl.edu
Persistent Ag induces a dysfunctional CD8 T cell state … TIM3+CX3CR1+ cells via a
TIM3−CX3CR1+ intermediate (Fig. 4H… % of CX3CR1+ CD8 T cells in the peripheral blood became …

[图书][B] CX3CR1: Re-Defining Exhausted CD8+ T Cell Populations

M ElJalby - 2017 - search.proquest.com
… CX3CR1 is induced on antigen-specific T cells in persistent … These capacities unique to
memory CD8+ T cells maintain … was hence named peripheral memory T (TPM) cells, and may …

Defining memory CD8 T cell

MD Martin, VP Badovinac - Frontiers in immunology, 2018 - frontiersin.org
persist in greater numbers (9); can populate peripheral organs (10); are poised to … subset
was described following the identification of Cx3Cr1 int peripheral memory (Tpm) T cells (43). …

CX3CR1+CD8+ T cells: Key players in antitumor immunity

J Ma, Y Wu, S Wu, Z Fang, L Chen, J Jiang… - Cancer …, 2024 - Wiley Online Library
… Effectively controlling the progression of chronic viral infections and tumor growth hinges …
Induction and maintenance of CX3CR1- intermediate peripheral memory CD8(+) T cells by …

[HTML][HTML] Inflammescent CX3CR1+ CD57+ CD8+ T cells are generated and expanded by IL-15

SR Morris, B Chen, JC Mudd, S Panigrahi, CL Shive… - JCI insight, 2020 - ncbi.nlm.nih.gov
… Here we characterized peripheral blood CD8 + T cells in … of bystander CD8 + T cell activation
and expansion in chronic untreated … Thus, in a mixed pool of CD8 + T cells, IL-15 induced