[HTML][HTML] Infant rhesus macaque brain α-tocopherol stereoisomer profile is differentially impacted by the source of α-tocopherol in infant formula
Background: α-tocopherol (αT) in its natural form [2´ R, 4´ R, 8´ RαT (RRR-αT)] is more
bioactive than synthetic α-tocopherol (all rac-αT). All rac-αT is widely used in infant formulas,
but its accretion in formula-fed infant brain is unknown. Objective: We sought to compare αT
and stereoisomer status in infant rhesus macaques (Macaca mulatta) fed infant formula
(RRR-αT or all rac-αT) with a reference group fed a mixed diet of breast milk and maternal
diet. Methods: From 1 d after birth until 6 mo of age, infants (n= 23) were either nursery …
bioactive than synthetic α-tocopherol (all rac-αT). All rac-αT is widely used in infant formulas,
but its accretion in formula-fed infant brain is unknown. Objective: We sought to compare αT
and stereoisomer status in infant rhesus macaques (Macaca mulatta) fed infant formula
(RRR-αT or all rac-αT) with a reference group fed a mixed diet of breast milk and maternal
diet. Methods: From 1 d after birth until 6 mo of age, infants (n= 23) were either nursery …
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