The objective of the present study was to investigate the influence of the encapsulation
efficiency and size of liposome on the oral bioavailability of griseofulvin-loaded liposomes.
Griseofulvin-loaded liposomes with desired characteristics were prepared from pro-
liposome using various techniques. To study the effect of encapsulation efficiency, three
preparations of griseofulvin, namely, griseofulvin aqueous suspension and two griseofulvin-
loaded liposomes with different amounts of griseofulvin encapsulated [ie, F1 (32%) and F2 …