Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in
human populations despite widespread herd immunity. Understanding viral mechanisms
that enable antigenic evolution is critical for designing durable vaccines and therapeutics.
Here, we utilize the primerID method of error-correcting viral population sequencing to
reveal an unexpected role for hemagglutinin (HA) glycosylation in compensating for fitness
defects resulting from escape from anti-HA neutralizing antibodies. Antibody-free …

Correction: Influenza A virus hemagglutinin glycosylation compensates for antibody escape
fitness costs … Correction: Influenza A virus hemagglutinin glycosylation compensates for
antibody escape fitness costs … (2018) Influenza A virus hemagglutinin glycosylation
compensates for antibody escape fitness costs. PLoS Pathog 14(1): e1006796. https://doi.org/10.1371/journal.ppat.1006796 …