Inhibition of corneal neovascularization with a nutrient mixture containing lysine, proline, ascorbic acid, and green tea extract

Y Shakiba, A Mostafaie - Archives of medical research, 2007 - Elsevier
Corneal neovascularization is a significant, sight-threatening complication of many ocular
surface disorders. Various growth factors and proteinases are involved in corneal
neovascularization. The data supporting a causal role for vascular endothelial growth factor
(VEGF) and matrix metalloproteinases (MMPs) are extensive. Inhibition of VEGF and MMPs
is a main strategy for treating corneal neovascularization. Several findings have shown that
corneal neovascularization can be reduced by using anti-VEGF and anti-MMPs agents …
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