[HTML][HTML] Inhibitory effect of silibinin on hepatitis B virus entry
Hepatitis B virus (HBV) infection is a worldwide health problem because of its potential to
cause liver cirrhosis and hepatocellular carcinoma. Silibinin is a constituent of an extract of
milk thistle, which is empirically used as a herbal medicine for the protection of liver, but its
detailed effects on HBV are unknown. Because a previous study reported that silibinin
hinders clathlin-mediated endocytosis (CME), we aimed to test whether silibinin inhibits the
entry of HBV into hepatocytes. Using HepG2-NTCP-C4 cells, which overexpress sodium …
cause liver cirrhosis and hepatocellular carcinoma. Silibinin is a constituent of an extract of
milk thistle, which is empirically used as a herbal medicine for the protection of liver, but its
detailed effects on HBV are unknown. Because a previous study reported that silibinin
hinders clathlin-mediated endocytosis (CME), we aimed to test whether silibinin inhibits the
entry of HBV into hepatocytes. Using HepG2-NTCP-C4 cells, which overexpress sodium …
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