Objective The role of innate immunity in Chlamydia‐induced arthritis has not been defined.
The purpose of this study was to examine the role of neutrophils in experimental arthritis in
mice with targeted elimination of the small GTPases Rac1 and Rac2, as well as the role of
Toll‐like receptors (TLRs) in this model. Methods Arthritis was induced by intraarticular
inoculation of synoviocyte‐packaged Chlamydia trachomatis. The degree of arthritis was
assessed according to joint swelling and pathology scores. The persistence of Chlamydia in …

ScholarWorks@Hanyang University: Innate immunity and arthritis: neutrophil Rac and Toll
like receptor 4 expression define outcomes in infection triggered arthritis … Innate immunity
and arthritis: neutrophil Rac and Toll like receptor 4 expression define outcomes in infection
triggered arthritis …