Interaction profiles of central nervous system active drugs at human organic cation transporters 1–3 and human plasma membrane monoamine transporter
TJF Angenoorth, S Stankovic, M Niello, M Holy… - International Journal of …, 2021 - mdpi.com
Many psychoactive compounds have been shown to primarily interact with high-affinity and
low-capacity solute carrier 6 (SLC6) monoamine transporters for norepinephrine (NET;
norepinephrine transporter), dopamine (DAT; dopamine transporter) and serotonin (SERT;
serotonin transporter). Previous studies indicate an overlap between the inhibitory
capacities of substances at SLC6 and SLC22 human organic cation transporters (SLC22A1–
3; hOCT1–3) and the human plasma membrane monoamine transporter (SLC29A4; …
low-capacity solute carrier 6 (SLC6) monoamine transporters for norepinephrine (NET;
norepinephrine transporter), dopamine (DAT; dopamine transporter) and serotonin (SERT;
serotonin transporter). Previous studies indicate an overlap between the inhibitory
capacities of substances at SLC6 and SLC22 human organic cation transporters (SLC22A1–
3; hOCT1–3) and the human plasma membrane monoamine transporter (SLC29A4; …
以上显示的是最相近的搜索结果。 查看全部搜索结果