International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

A Bal-Price, KM Crofton, M Leist, S Allen, M Arand… - Archives of …, 2015 - Springer
A major problem in developmental neurotoxicity (DNT) risk assessment is the lack of
toxicological hazard information for most compounds. Therefore, new approaches are being
considered to provide adequate experimental data that allow regulatory decisions. This
process requires a matching of regulatory needs on the one hand and the opportunities
provided by new test systems and methods on the other hand. Alignment of academically
and industrially driven assay development with regulatory needs in the field of DNT is a core …

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

M Leist, T Hartung - 2015 - kops.uni-konstanz.de
A major problem in developmental neurotoxicity (DNT) risk assessment is the lack of
toxicological hazard information for most compounds. Therefore, new approaches are being
considered to provide adequate experimental data that allow regulatory decisions. This
process requires a matching of regulatory needs on the one hand and the opportunities
provided by new test systems and methods on the other hand. Alignment of academically
and industrially driven assay development with regulatory needs in the field of DNT is a core …
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