This chapter reveals the overview of the Internet of Things (IoT); the IoT, Wireless Sensor Networks (WSNs), and Radio Frequency Identification (RFID); the technology of the IoT; the IoT and security concerns; the information security aspects of the IoT; the applications of the IoT in modern health care; and the implications of the IoT in the digital age. Organizations can utilize the IoT to gain the considerable cost savings by improving asset utilization, enhancing process efficiency, and increasing productivity in global operations. However, the IoT has its own challenges, such as the privacy of personal data, the lack of compatibility, and security breach. The chapter argues that utilizing the IoT and security techniques has the potential to enhance organizational performance and meet security requirements toward threat prevention in global operations.