Interpretation of positive molecular tests of common viruses in the cerebrospinal fluid
A Bhaskaran, L Racsa, R Gander, P Southern… - … and Infectious Disease, 2013 - Elsevier
Many central nervous system infections are historically difficult to diagnose. Polymerase
chain reaction (PCR) has revolutionized the diagnosis of these infections because of their
high sensitivity despite the lack of data on clinical usefulness. We conducted a retrospective
study that included patients with positive cerebrospinal fluid (CSF) PCR for herpes simplex
virus, varicella-zoster virus, JC virus, cytomegalovirus (CMV), and Epstein-Barr virus (EBV)
between January 2009 and December 2011. The positive results were grouped into definite …
chain reaction (PCR) has revolutionized the diagnosis of these infections because of their
high sensitivity despite the lack of data on clinical usefulness. We conducted a retrospective
study that included patients with positive cerebrospinal fluid (CSF) PCR for herpes simplex
virus, varicella-zoster virus, JC virus, cytomegalovirus (CMV), and Epstein-Barr virus (EBV)
between January 2009 and December 2011. The positive results were grouped into definite …
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