Intestinal anastomotic injury alters spatially defined microbiome composition and function

BD Shogan, DP Smith, S Christley, JA Gilbert… - Microbiome, 2014 - Springer
Background When diseased intestine (ie, from colon cancer, diverticulitis) requires
resection, its reconnection (termed anastomosis) can be complicated by non-healing of the
newly joined intestine resulting in spillage of intestinal contents into the abdominal cavity
(termed anastomotic leakage). While it is suspected that the intestinal microbiota have the
capacity to both accelerate and complicate anastomotic healing, the associated genotypes
and functions have not been characterized. Results Using 16S rRNA amplicon sequencing …

[引用][C] Intestinal anastomotic injury alters spatially defined microbiome composition and function. Microbiome. 2014; 2: 35

BD Shogan, DP Smith, S Christley, JA Gilbert…
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