Intramolecular [1,4]-S- to O-Silyl Migration: A Useful Strategy for Synthesizing Z-Silyl Enol Ethers with Diverse Thioether Linkages
An intramolecular [1, 4]-S-to O-silyl migration has been used to form silyl enol ethers with Z-
configurational control. The silyl migration also creates a new anion center at sulfur, which
can subsequently react with electrophiles to generate Z-silyl enol ethers with diverse
thioether linkages. The synthetic utility of this pathway was demonstrated by modifying the Z-
silyl enol ethers with aldehydes via a Mukaiyama aldol reaction or Prins cyclization to
generate functionalized organosulfur compounds.
configurational control. The silyl migration also creates a new anion center at sulfur, which
can subsequently react with electrophiles to generate Z-silyl enol ethers with diverse
thioether linkages. The synthetic utility of this pathway was demonstrated by modifying the Z-
silyl enol ethers with aldehydes via a Mukaiyama aldol reaction or Prins cyclization to
generate functionalized organosulfur compounds.
[引用][C] Intramolecular [1, 4]-S-to O-Silyl Migration: A Useful Strategy for Synthesizing Z-Silyl Enol Ethers with Diverse Thioether Linkages
S Changzhen, Z Yuebao, X Peihong, L Hongze… - 2014
以上显示的是最相近的搜索结果。 查看全部搜索结果