Intranasal administration for pain: oxytocin and other polypeptides

VN Bharadwaj, AZ Tzabazis, M Klukinov, NA Manering… - Pharmaceutics, 2021 - mdpi.com
… reach the CSF and brain tissue and briefly discuss the nasal–… IN delivery of oxytocin for
trigeminal and chronic pain. Lastly, we review the literature on other IN applied polypeptides that …

[PDF][PDF] Intranasal Administration for Pain: Oxytocin and Other Polypeptides. Pharmaceutics 2021, 13, 1088

VN Bharadwaj, AZ Tzabazis, M Klukinov, NA Manering… - 2021 - academia.edu
… reach the CSF and brain tissue and briefly discuss the nasal–… IN delivery of oxytocin for
trigeminal and chronic pain. Lastly, we review the literature on other IN applied polypeptides that …

Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action

S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
… contribution of different methods of intranasal application and … functional effects of intranasal
oxytocin and vasopressin in … into the brain following intranasal administration, others may be …

Oromucosal Administration of Oxytocin: The Development of 'Oxipops'

D Xu, C Lan, J Kou, S Yao, W Zhao, KM Kendrick - Pharmaceutics, 2024 - mdpi.com
pain [10]. To date, all randomized clinical trials have chosen to use an intranasal route for
the chronic administration of oxytocin … routes whereby intranasally administered oxytocin can …

Oxytocin analogues for the oral treatment of abdominal pain

T Kremsmayr, G Schober, M Kaltenböck… - Angewandte Chemie …, 2024 - Wiley Online Library
… [15a, 15b] In line 27 with this, administration of exogenous OT increases pain perception …
abdominal discomfort and pain under conditions 29 of chronic constipation (intranasal delivery).…

Prolactin and oxytocin

S Lo-Cascio, C Börner, M Kodounis, S Ratti… - 2023 - dadun.unav.edu
… using intranasal administration of oxytocin, or possibly other … release of PRL, such as
polypeptide PRL-releasing factor, 5-… pain intensity at two hours after intranasal OT administration. …

Intranasal oxytocin alleviates comorbid depressive symptoms in neuropathic pain via elevating hippocampal BDNF production in both female and male mice

R Liu, D Sun, X Xing, Q Chen, B Lu, B Meng, H Yuan… - …, 2024 - Elsevier
… or spinal administration. Because of the advantage of intranasal delivery of oxytocin in …
the effect of intranasal application of oxytocin on neuropathic pain and comorbid depressive …

Influence of oxytocin on the central nervous system by different routes of administration

MV Litvinova, AA Lebedev… - …, 2023 - journals.eco-vector.com
… of oxytocin did not show significant changes in behavior compared with the control group. In
addition, after intranasal administration of oxytocin… of intranasal administration of oxytocin in …

Impact of magnesium on oxytocin receptor function

VN Bharadwaj, J Meyerowitz, B Zou, M Klukinov, N Yan… - Pharmaceutics, 2022 - mdpi.com
… Background and Purpose: The intranasal administration of oxytocin (OT) reduces … to other
tissue regions [20,24]. We have also shown that intranasal OT inhibits the transmission of pain

Oxytocin and positive couple interaction affect the perception of wound pain in everyday life

AC Pfeifer, P Schroeder-Pfeifer, E Schneider… - … pain, 2020 - journals.sagepub.com
… by showing that a single dose of intranasally administered OT can affect stress regulation and
… Our results suggest that intranasal OT reduced pain experiences to an ecological valid yet …