Intrinsic functional network connectivity is associated with clinical symptoms and cognition in late-life depression
JA Gandelman, K Albert, BD Boyd, JW Park… - Biological Psychiatry …, 2019 - Elsevier
Background Late-life depression (LLD) has been associated with alterations in intrinsic
functional networks, best characterized in the default mode network (DMN), cognitive control
network (CCN), and salience network. However, these findings often derive from small
samples, and it is not well understood how network findings relate to clinical and cognitive
symptomatology. Methods We studied 100 older adults (n= 79 with LLD, n= 21
nondepressed) and collected resting-state functional magnetic resonance imaging, clinical …
functional networks, best characterized in the default mode network (DMN), cognitive control
network (CCN), and salience network. However, these findings often derive from small
samples, and it is not well understood how network findings relate to clinical and cognitive
symptomatology. Methods We studied 100 older adults (n= 79 with LLD, n= 21
nondepressed) and collected resting-state functional magnetic resonance imaging, clinical …
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