Iron (III) trifluoroacetate [Fe (O2CCF3) 3] catalyzed epoxide opening with amines
E Erturk, AS Demir - 2008 - open.metu.edu.tr
E Erturk, AS Demir
2008•open.metu.edu.trNon-hygroscopic, non-toxic, and readily available iron (III) trifluoroacetate [Fe (O2CCF3)(3)]
was found to be a highly regioselective catalyst for the ring opening of a wide variety of
epoxides with diverse amines under solvent-free conditions. The stereospecific ring opening
of (R)-styrene oxide (4) with p-anisidine (2b) in the presence of 1 mol% of Fe (O2CCF3)(3)
gave 2-(p-methoxyphenyl-amino)-2-phenylethanol (5b) in enantiopure form (> 99% ee)
within 60 minutes.
was found to be a highly regioselective catalyst for the ring opening of a wide variety of
epoxides with diverse amines under solvent-free conditions. The stereospecific ring opening
of (R)-styrene oxide (4) with p-anisidine (2b) in the presence of 1 mol% of Fe (O2CCF3)(3)
gave 2-(p-methoxyphenyl-amino)-2-phenylethanol (5b) in enantiopure form (> 99% ee)
within 60 minutes.
Non-hygroscopic, non-toxic, and readily available iron(III) trifluoroacetate [Fe(O2CCF3)(3)] was found to be a highly regioselective catalyst for the ring opening of a wide variety of epoxides with diverse amines under solvent-free conditions. The stereospecific ring opening of (R)-styrene oxide (4) with p-anisidine (2b) in the presence of 1 mol% of Fe(O2CCF3)(3) gave 2-(p-methoxyphenyl-amino)-2-phenylethanol (5b) in enantiopure form (> 99 % ee) within 60 minutes.
open.metu.edu.tr
以上显示的是最相近的搜索结果。 查看全部搜索结果