dividing bacilli but also the dormant bacilli during persistent infection. Isocitrate lyase (ICL) is
a key enzyme of the glyoxylate shunt, crucial for the survival of bacteria in macrophages and
mice. MtbICL is considered as one of the potential and attractive drug targets against
persistent infection. We report the inhibition of MtbICL by quercetin with IC 50 of 3.57 μM. In
addition, quercetin strongly inhibited the growth of Mtb H37Rv utilizing acetate, rather than …