Isolated hevein-like domains, but not 31-kd endochitinases, are responsible for IgE-mediated in vitro and in vivo reactions in latex-fruit syndrome
P Karisola, A Kotovuori, S Poikonen, E Niskanen… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: Individuals with natural rubber latex allergy often have immediate reactions
to plant-derived foods and fresh fruits, such as avocado and banana. IgE of these patients
has been shown to bind endochitinases containing an N-terminal hevein-like domain (HLD).
However, evidence on 31-kd endochitinase-induced reactions in vivo is lacking.
OBJECTIVE: We sought to assess the clinical significance of 31-kd endochitinases and
isolated HLDs in latex-fruit syndrome. METHODS: The 31-kd endochitinases and …
to plant-derived foods and fresh fruits, such as avocado and banana. IgE of these patients
has been shown to bind endochitinases containing an N-terminal hevein-like domain (HLD).
However, evidence on 31-kd endochitinase-induced reactions in vivo is lacking.
OBJECTIVE: We sought to assess the clinical significance of 31-kd endochitinases and
isolated HLDs in latex-fruit syndrome. METHODS: The 31-kd endochitinases and …
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