JUMPn: a streamlined application for protein co-expression clustering and network analysis in proteomics

D Vanderwall, P Suresh, Y Fu, JH Cho, TI Shaw… - JoVE (Journal of …, 2021 - jove.com
With recent advances in mass spectrometry-based proteomics technologies, deep profiling
of hundreds of proteomes has become increasingly feasible. However, deriving biological
insights from such valuable datasets is challenging. Here we introduce a systems biology-
based software JUMPn, and its associated protocol to organize the proteome into protein co-
expression clusters across samples and protein-protein interaction (PPI) networks
connected by modules (eg, protein complexes). Using the R/Shiny platform, the JUMPn …

[引用][C] Jumpn: a streamlined application for protein co-expression clustering and network analysis in proteomics

V David, S Poudel, F Yingxue, C Ji-Hoon, M Ashutosh… - 2021
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