Previous studies investigating the role of smooth muscle cells (SMCs) and macrophages in
the pathogenesis of atherosclerosis have provided controversial results owing to the use of
unreliable methods for clearly identifying each of these cell types. Here, using Myh11-
CreERT2 ROSA floxed STOP eYFP Apoe−/− mice to perform SMC lineage tracing, we find
that traditional methods for detecting SMCs based on immunostaining for SMC markers fail
to detect> 80% of SMC-derived cells within advanced atherosclerotic lesions. These …

… This corrects the article "KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key
Role in Atherosclerotic Plaque Pathogenesis" in Nat Med, volume 21 on page 628. … Also,
in Figure 4g, MKi67, used as a cell proliferation marker, is misspelled. The errors have been
corrected in the HTML and PDF versions of the article. …